Chris Rosser BlueJay 2024: https://youtu.be/EhYKeZfSQIw (Caveat: Bluejay devs seem to recommend 48khz, and also recommend do not set startup powers to max)
As MOSFET switching frequency increases, so does heat generation.
Some reports exist of too hot ESC's/Motors at 128khz PWM depending on the brand/model of the ESC/Motors.
Desyncs
Desyncs are typically a factor of ESC settings.
Set Motor Timing to a some static value of personal preference. 23 is good for freestyle. Racers typically use higher values.
Demag Compensation also a factor but try static timing first, and increase Demag-Comp only as much as needed to resolve.
Racing Considerations
Demag compensation low saves roughly 7K RPM (20%) on high kv motors. Although off versus low has minimal effect, some prefer OFF. Thanks to @FreedomDuck for this information. (Ultralight 6S 2100kv to 2150kv.)
Some BLHeli_32 ESC's can be flashed with with other firmware, but requires STLink or similar devices and bootloader unlocking. Search for AM32 and/or Escape32 resources on the subject.