nf-core/genomeassembler assembly validation and curation discussion

Desired components:

• K-mer copy number spectra profile - Merqury
• Contamination profile - Blobtools
• Gene space checks - Busco ( Dogma too?)
• Assembly comparison and stats - Quast
• Other accuracy metrics ( Inspector ? FRCBam ? )
• Pairwise genome plots
• Assembly graph plots ( Bandage )
• Read coverage ( Qualimap, Blobtools )
• Output genome browser tracks with useful information, like polished areas, missassembly signals, coverage, etc

Workflow diagram draft:

Implementations:

• Pairwise genome comparison workflow
• Generate list of pairwise inputs:
  ​​workflow {
  ​​  Channel.of( 'A', 'B', 'C' )
  ​​      .toSortedList()
  ​​      .flatMap {
  ​​          it.subsequences()
  ​​              .findAll { it.size() == 2 }
  ​​      }.view()
  ​​  // Output is [B, C], [A, B], [A, C]
  ​​}