$AVAX C-Chain is EVM compatible, so you can use Web3.py with $AVAX in the same way would with Ethereum.
It’s commonly found in decentralized apps (dapps) to help with sending transactions, interacting with smart contracts, reading block data, and a variety of other use cases.
There's a public API / node provided for the C-Chain (details here), here's an quick example to get started:
A few more things: