# Comparing different models to BUSTED-PH

### PG-BSM
* A Phenotype–Genotype Codon Model for Detecting Adaptive Evolution
* Christopher T Jones, Noor Youssef, Edward Susko, Joseph P Bielawski
* This is a sites model, focused more on nonadaptive shifting balance than adaptive evolution. Does this by finding an
* Invertebrate cytochrome b- in mitochondria, highly conserved. Expected positive selection for transition from marine to other environments
* terrestrial versus nonterrestrial, freshwater versus nonfreshwater, and intertidal versus nonintertidal
* Two other alignments: phytochrome data (plants) and mammalian mtDNA (primates vs nonprimates)
### COEVOL
* Paper: Genomic Signature of an Avian Lilliput Effect across the K-Pg Extinction
* Jacob S. Berv, Daniel J. Field
* Included a table full of trait values: mass_g, avg_maturity_days, gestation_incubation_days, clutch_size_per_year, birth_mass_g, growth_rate, longevity_yrs, metabolic_rate_w
* Only mass_g was complete, other traits had lots of missing data
* Took top 20% of mass values, put them in the foreground. Will have to compare this to the future model of busted-ph with continuous phenotypes
### RERconverge
* Skipping this because of our collaboration, RERconverge will probably be in the paper anyway
### TraitRate[Prop]
* Paper: What snakes and caecilians have in common? Molecular interaction units and the independent origins of similar morphotypes in Tetrapoda
* Anieli G. Pereira, Mariana B. Grizante and Tiana Kohlsdor
* Foreground species were defined as the ones characterized by the RAL morphotype the lumbar region corresponds to a posterior extension of the thorax exhibiting vertebrae with associated ribs in this region
* HOXA10 gene
### Forward Genomics
**This model does not use fastas, it uses a percent identity calculation. therefore i do not think it can be directly compared to busted-ph**
* Vision-related convergent gene losses reveal SERPINE3’s unknown role in the eye ==> **the tree used from this paper made no sense.**
*
* Henrike Indrischek, Juliane Hammer, Anja Machate, Nikolai Hecker, Bogdan Kirilenko, Juliana Roscito, Stefan Hans, Caren Norden, Michael Brand, Michael Hiller
* Authors of paper include some of coevolve’s original authors
* Mostly relaxation of selection, not expected to see positive selection
* Used UCSC data which we have had issues with. So I have a backup paper
### Phyloacc
* Every paper I’ve looked at has used phyloacc for noncoding regions so I could not include this model.
* Maybe it could be better compared to RERconverge
### Trait RELAX
* A Codon Model for Associating Phenotypic Traits with Altered Selective Patterns of Sequence Evolution
* Keren Halabi, Eli Levy Karin, Laurent Guéguen, Itay Mayrose
* https://academic.oup.com/sysbio/article/70/3/608/6012374?login=false
* Semenogelin II (SEMG2) in 24 primate species with respect to changes in the mating system
* 68 genes from 50 species of γ-proteobacteria, of which 36 are free living and 14 are endosymbionts were examined.