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title: Endfeet
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title: Endfeet
disqus: hackmd
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Endfeet
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> Documentation [name=MrDr.Staffan]
###### tags: `page`, `endfeet`
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### Table of Contents
[TOC]
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[Top](#Table-of-Contents)

**Why this page?**
Endfeet

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See

Restraction by laser ablation. (or FRAPing?)
https://www.nature.com/articles/s41598-018-37419-4




# Endfeet Simon 2018
[2018 J Neurosci Res. A transcriptome-based assessment of the astrocytic dystrophin associated complex in the developing human brain](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995340/)

dystrophin associated complex (DAC) is what is being looked at.

" human transcriptome data from male and female subjects across several developmental stages and brain regions to characterize the gene expression profile of the dystrophin associated complex (DAC), a known structural component of the astrocytic endfoot that supports perivascular localization of the astroglial water channel aquaporin-4 (AQP4)"

Includes Slc9a3r1 

## Dtna
[![](https://i.imgur.com/ZV7pIPR.jpg "DTNA" =200x)](https://www.proteinatlas.org/ENSG00000134769-DTNA/tissue/basal+ganglia#img)





# Boulay AC 2019
[See Data RNAseq_Mm_AstrocyteEndFeet](https://docs.google.com/spreadsheets/d/1UK5-CQIvNXKXGvyeegkGSg0yy_qjVSQT9agwiE52myY/edit#gid=1918952779)

Astrocyte endfeet perivascular membranes remain attached to mechanically isolated brain vessels. Mild BL enzymatic digestion might detach them and possibly deplete brain vessels of astrocyte perivascular mRNAs

=> [Many of these are Ependymal markers]

