# Spravato: Advanced Relief for Treatment-Resistant Depression At Lotus Psychiatry and Wellness, we understand that living with depression—especially treatment-resistant depression (TRD)—can be exhausting and overwhelming. That’s why we proudly offer Spravato, a revolutionary, FDA-approved therapy designed for adults who haven’t found relief with traditional antidepressants. Administered in a safe, clinical setting under medical supervision, **[Spravato](https://lotuspsychiatryandwellness.com/spravato/)** (esketamine) provides fast-acting relief and renewed hope for patients struggling with severe depression. ## How Spravato Works Unlike traditional antidepressants that target serotonin, Spravato affects the brain's glutamate system, helping to restore synaptic connections and improve communication between brain cells. This unique mechanism allows Spravato to deliver rapid relief from depressive symptoms, often within hours or days rather than weeks. Spravato is a nasal spray that is administered in-office under the care of a certified provider. It is used in combination with a daily oral antidepressant and is especially beneficial for individuals with major depressive disorder (MDD) who have tried multiple medications without success. ## Who Is a Candidate for Spravato? Spravato may be the right treatment for you if: You have been diagnosed with treatment-resistant depression You’ve tried at least two different antidepressants with minimal or no relief You are experiencing major depressive disorder with suicidal thoughts or behaviors You’re seeking a new treatment option that works differently than traditional medications At Lotus Psychiatry and Wellness, we perform a detailed psychiatric evaluation to determine if you’re an appropriate candidate for Spravato therapy. ## What to Expect During Spravato Treatment Spravato treatments are administered in our certified treatment facility. Each session includes: Self-administration of the nasal spray under medical supervision Observation period of about two hours to monitor for side effects and ensure safety Comfortable and private setting to support a calming treatment experience During the initial phase, treatments are typically administered twice per week for four weeks, followed by a gradual reduction in frequency based on your response and progress. Most patients report feeling improvements in mood, energy, and emotional clarity within the first few treatments. ## Why Choose Lotus Psychiatry and Wellness for Spravato Treatment? As a certified Spravato treatment center, Lotus Psychiatry and Wellness is committed to delivering compassionate, effective, and personalized care. Our approach includes: Board-Certified Psychiatrists with experience in TRD and ketamine-based therapies Customized care plans tailored to your mental health needs Safe, structured clinical environment with close monitoring Insurance support to help make treatment more affordable Ongoing support throughout your recovery journey Our team is dedicated to helping you regain control of your life with advanced mental health solutions. ### Start Your Journey to Healing Today If you’re ready to try something different in your fight against depression, **[Spravato](https://lotuspsychiatryandwellness.com/spravato/)** may be the answer. At Lotus Psychiatry and Wellness, we offer compassionate, expert-led care using the most innovative treatments available. Contact us today to schedule a consultation and find out if Spravato is right for you.