# Patho Micro Block II
## Immunological disorder
### Vol 13
* 一. PA0030 (25)Amyloidoma, lung, 54F(P.3)
* amorphous, hyaline, extracellular deposits
* 裂縫
* histiocyte & multinucleate giant cells
* 二. PA0061 (43)Acute cellular rejection, liver, 49F (P.26)
* mixed portal inflammatory infiltrate
* bile duct injury (上皮受傷): 發炎細胞浸潤 & 上皮受損 (質紅有小泡和排列不規則)
* endotheliitis (小血管受傷): 發炎細胞 & 內皮受損 (lifted from basement membrane)
* 三. PA0086 (69) Chronic rejection, kidney, 57F(P.43)
* T-cell mediated
* tubulointerstitial pattern: tubilitis (mononuclear cells) & interstitial inflammation (lymphocytes)
* vascular pattern: endotheliitis (lymphocytes)
* Antibody mediated
* glomerulitis (mononuclear cells) & peritubular capillaritis (neutrophil or mononuclear cells)
* Chronic
* intimal thicken with inflammatory infiltration
* glomerulopathy
* interstitial fibrosis
* 四. PA0261(191) Pneumocystis jiroveci pneumonia (P.75)
* intra-alveolar eosinophilic foamy proteinaceous material with pneumocystis jiroveci trophic form
* type II pneumocyte hyperplasia & chronic interstitial septum fibrosis
* 五. PA0264 (193)Allergic rhinitis (P.105)
* basement membrane thickening
* 發炎浸潤: lymphocyte, plasma cell, eosinophilic (allergic)
* squamous metaplasia
## Childhood disease
### Vol 14
* 一. PA0085 (68) Nephroblastoma (Wilms’ tumor), soft tissue(kidney)
* triphasic: blastemal, stromal, epithelial
* blastemal: 小藍圓
* stromal: spindle
* epithelial: 像壞掉的 tubules 或 glomeruli structure,圍成 lumen
* 二. PA0131 (107) Neuroblastoma, adrenal gland
* 小藍圓 (-blastoma)
* neuronal differentiation:
* neuroblast: neuropil 背景, Homer-Wright pseudorosettes
* ganglion cells: 核偏心
### Vol 15
* ~~PA0247~~ PA0167, PA0168, PA0196 (142) Retinoblastoma, eye
* 小藍圓
* Flexner-Wintersteiner rosette
* Fleurette
* PA0200 (146) Hyaline membrane disease, lung
* eosinophilic hyaline membrane: fibrin + cell debris
* collapsed alveoli
* Teratoma
* 呼吸上皮、角質化鱗狀上皮、皮脂腺、毛囊
## Epithelial tumor
### Vol 16
* 一. PA0046 (31) Pleomorphic adenoma (mixed tumor), parotid gland
* epithelial + mesenchyme element
* Epithelial
* duct: ductal cell + myoepithelium (核偏心像 plasma cell, cytoplasm 空亮 clear, spindled or epithelioid [cuboid])
* Mesenchymal
* modified myoepithelium
* myxod
* 二. PA0047 (32) Squamous cell carcinoma, esophagus
* invasive
* squamous eddy, keratinization, intercellular bridge
* LOSS of nuclear orientation and maturation
* 三. PA0249 (38) Adenocarcinoma, colon
* glandular differentiation
### Vol 17
* 一. PA0101 (82) High-grade squamous intraepithelial lesion, cervix, 43F
* 沒有侵犯: 侷限在基底膜以上
* 二. PA0102 (83) Squamous cell carcinoma, uterine cervix, 61F
### Vol 18
* 一. PA0142 (118) Basal cell carcinoma, lip, 83M
* 二. PA0207 (151) Familial adenomatous polyposis, large intestine, 20F
## Mesenchymal tumor
### Vol 19
* 一. PA0100 (81) Malignant melanoma, vulva, 55F
* 二. PA0104 (85) Leiomyoma, uterus, 43F
* 三. PA0154(130) Desmoid-type fibromatosis (Desmoid tumor), soft tissue (abdominal wall), 35F
### Vol 20
* 一. PA0257 (131)Myxoid liposarcoma, thigh, soft tissue (p.3)
* chicken-wired capillaries
* lipoblast
* 二. PA0156 (132)Lymphangioma, soft tissue (leg) (p.22)
* 三. PA0195 (134)Neurofibroma, plexiform and diffuse, cheek (p.36)
### Vol 21
* 一. PA0158 (135) Schwannoma, soft tissue, near T-level vertebra(P.3)
* Antoni A, B
* 二. PA0226 (167) Embryonal rhabdomyosarcoma, soft tissue(P.33)
* primitive round and spindled cell
* 三. PA0107 (88) Mature cystic teratoma, ovary(P.49)
## Cardiovascular system
### Vol 22
* 一. PA0170 (2)Atherosclerosis, 68M (P.3)
* 二. DEMO:PA0169 Atherosclerosis, 57M, heart, coronary artery(P.23)
* 三. PA0171 (3)Amyloidosis, myocardium (P.26)
### Vol 23
* 一. PA0001 (4) Infective endocarditis, mitral valve, 60M (P.3)
* 二. PA0004 (6) Myocardial infarction, heart, 54M(P.13)
* 三. PA0002 (5) Cardiac myxoma, heart, left atrium, 68F (P.34)
* 四. PA0197 (143)Acute rheumatic pancarditis(P.49)
* 五. PA0266 Cavernous hemangioma(embryonal rhabdomyosarcoma; soft tissue) (老師投影片誤植成 PA0226) (P.73)
## Respiratory system
### Vol 24
* 一. PA0174(19)Adenocarcinoma, lung, 58M(P.4)
* 二. PA0018(20)Small cell carcinoma, soft tissue(lung), 82M(P.19)
* 三. PA0021 (22) Squamous cell carcinoma, lung, 60M (p.25)
* 四. PA0023 (23) Invasive mucinous adenocarcinoma, lung, 78F(p.49)
### Vol 25
* 一. PA0024(24)Bronchopneumonia, lung, 72F(P.3) (& Diffuse alveolar damage)
* 二. PA0040(26)Diffuse alveolar damage, lung, 52M(P.27)
* 三. PA0041(27)Mesothelioma, pleura, 56M(P.41)
* 四. PA0263(192)Pneumoconiosis (P.58)
## Summary
### 器官
* kidney: nephroblastoma (Wilm's tumor), chronic rejection
* lung: amyloidoma, hyaline membrane disease, diffuse alveolar damage, bronchopneumonia, small cell carcinoma, squamous cell carcinoma, adenocarcinoma, invasive mucinous adenocarcinoma
* PCP vs. hyaline membrane disease