Authors: Mengying Yan, Meng Xia, Wei A. Huang, Chuan Hong, Benjamin A. Goldstein, Matthew M. Engelhard
Affiliations: Duke AI Health, Department of Biostatistics and Bioinformatics, Department of Electrical and Computer Engineering, Duke University School of Medicine
Adversarial-Positive-Unlabeled-Domain=Adaptation
Understanding the Research
This research addresses a real-world challenge in healthcare: predicting long-term patient outcomes (e.g., 1-year mortality) in recent patient cohorts for whom such outcomes are not yet fully available. Traditional predictive models struggle when applied across time due to changes in clinical practice, patient populations, and label availability. To overcome this, the authors introduce an approach that combines adversarial domain adaptation and positive-unlabeled (PU) learning to enable prediction using partially labeled data.
Motivation
Predicting long-term outcomes is crucial in clinical settings, yet: