# Overview of bioinformatic analysis pipeline ![](https://hackmd.io/_uploads/HkVUqj1Fn.png) <center> Code is archived in [github repo](https://github.com/jlk666/CE_WGS). </center> # Quality Control of WGS Data ![](https://hackmd.io/_uploads/S1FC5Va_2.png) ![](https://hackmd.io/_uploads/BJi-sE6dh.png) # Genome Similarity Signature of each WGS data was generated using [Sourmash](https://github.com/sourmash-bio/sourmash). ![](https://hackmd.io/_uploads/rJTd7zRu2.png) ## *Lactoccocus* isolates potential gene producing bacteriocin ![](https://hackmd.io/_uploads/Skl7jo1F2.png) ![](https://hackmd.io/_uploads/BkcTijktn.png) The most significant hit was found in Nisin Z, which was documented to show promisingly effective [anti-microbial effects against clinically significant bacteria](https://www.futuremedicine.com/doi/10.2217/fmb-2019-0153). ## Rough validation results ![](https://hackmd.io/_uploads/SksAai1Kn.jpg)