--- tags: tier1 --- # Diabetes ## Definition 1. Fasting glucose greater than 126mg/dL 2. Random glucose >200mg/dL 3. A1c >6.5% x2 measurements ## Inpatient Diabetes :::warning Hold ALL ORAL meds on admission ::: First, figure out their total daily dose of insulin. If they're on insulin its just the sum of all the insulin they take every day. If they're not on insulin at home use **0.5U/kg** as a good starting TDD. ```graphviz digraph hierarchy { // increases the separation between nodes nodesep=0.8 //All nodes will this shape and colour node [color=Red,fontname=Helvetica,shape=box] edge [color=Blue, style=dashed] //All the lines look like this TDD[label = "TDD Insulin"]; Bolus[label = "Bolus (qAc)"]; Basal[label = "Basal (qHs)"]; TDD->{Bolus Basal} Basal->2100 Bolus->0800 0800->1200 1200->1800 // Put them on the same level {rank=same;Bolus Basal} } ``` :::danger If NPO, **hold bolus** insulin but always **give basal** ::: #### Steroid Hyperglycemia NPH is often used to treat steroid hyperglycemia in the hospital, its one of the few cases you'll see NPH used. Its kinetics conveniently match that of prednisone. Typically **0.5U/mg prednisone** (or pred equivalent) is a [good starting place](https://pubmed.ncbi.nlm.nih.gov/34420221/). ### Initial Treatment :::info On boards: firstline treatmen is typically *weightloss*. ::: After failing lifestyle modifications usually Metformin is tried next #### Insulin Types ![](https://i.imgur.com/HFfMaqa.png)