---
# System prepended metadata

title: GWAS turorial

---

# Advanced GWAS tutorial in Golden Retriever dogs  
**Date**: Jan 22-23, 2024 (9AM-5PM Pacific Time)
**Design**: Hybrid (You may attend in person at UC-Davis or join us via zoom)
**Expected capacity**: Up to 30 attendees (<ins>*Priority for attending in person*</ins>). 
**Instructors**: [Tamer Mansour](https://scholar.google.ca/citations?user=xo-4__IAAAAJ&hl=en), Mohamed Abuelanin, and Brenna Swafford
**Material link**: https://morrisanimalfoundation.github.io/grGWAS/

## Background:
The [Golden Retriever Lifetime Study](https://www.morrisanimalfoundation.org/golden-retriever-lifetime-study) is one of the largest, most comprehensive prospective canine health studies in the United States. The Study’s purpose is to identify the nutritional, environmental, lifestyle and genetic risk factors for cancer and other diseases in Golden Retriever dogs. You can learn more data collected by the study [here](https://datacommons.morrisanimalfoundation.org/node/221). 

## Why is this workshop different?
Effective participation in the workshop allows you to submit a follow up proposal to finish your GWAS analysis. In the follow up project, you will gain access to the most complete version of the phenotypic data. Also, you can get computational resources, bioinformatic support, and extra funding for a small sequencing project if needed. 


## Registration: 
Each attendant should create log-in credentials at the [MAF data portal](https://datacommons.morrisanimalfoundation.org/), choose a phenotype of interest and write a proposal for why the chosen phenotype is likely heritable. You will also need to define the inclusion and exclusion criteria of the subjects of the study. Please fill in your information [here](https://forms.gle/KBmXTPC6D9SWksZ77) (up to 1500 characters).


## Schedule 

### Day 1

|   Time   |  Topic    |
| ---- | ---- |
| 09:00-10:30 AM     |   Setup   |
| 10:30-10:45 AM     |   Coffee Break   |
| 10:45-12:00 AM     |   GRLS Phenotype Dataset   |
| 12:00-01:00 PM     |   Lunch Break   |
| 01:00-02:30 PM     |   GRLS Genotype Dataset   |
| 02:30-02:45 PM     |   Coffee Break   |
| 02:45-04:45 PM     |   Data QC & filtration   |
| 04:45-05:00 PM     |   Wrap up   |



### Day 2

| Time | Topic |
| -------- | -------- |
| 09:00-10:30 AM     |   Study design 1   |
| 10:30-10:45 AM     |   Coffee Break   |
| 10:45-12:00 AM     |   Study design 2   |
| 12:00-01:00 PM     |   Lunch Break   |
| 01:00-02:30 PM     |   Heritability analysis   |
| 02:30-02:45 PM     |   Coffee Break   |
| 02:45-04:45 PM     |   GWAS analysis   |
| 04:45-05:00 PM     |   Wrap up   |




## Computer requirements
We will use a UC Davis supercomputer to run the tutorial. However, attendees will need to bring a computer with a Web browser, an Internet connection, and an ssh client; Windows users should install [MobaXterm](https://mobaxterm.mobatek.net/) before the workshop.

