# Fears Fueled by Forums The concept of drug tolerance – where the body adapts to a medication over time, requiring higher doses to achieve the same effect – is a real phenomenon for some substances, particularly opioids or benzodiazepines. However, the degree and speed at which tolerance develops vary enormously between drug classes. As Dr. Evans, a urologist, I find that online health forums often paint a distorted picture, especially regarding "lifestyle" medications like those for erectile dysfunction. Myths and anxieties can take root, leading patients to anticipate problems that aren't pharmacologically likely, sometimes driving them to make preemptive, risky decisions. ![fildena 100 mg](https://hackmd.io/_uploads/Sy-BUmFlxg.png) # When Treatment Success Breeds Anxiety Mr. Carter, a man in his mid-forties, had been doing very well. A few months prior, we'd started him on generic sildenafil 50mg for his ED. He reported consistent efficacy, good results that significantly improved his confidence and relationship, and only minimal initial side effects (mild headache) that had largely faded. By all measures, it was a successful and stable treatment plan. So, I was surprised when he booked an unscheduled appointment, arriving looking distinctly uncomfortable. "Doc," he began, shifting in his seat, "It's the side effects. They've gotten really bad lately. Whenever I take the pill now, I get these pounding headaches, my face gets beet red and feels hot for hours, and my stomach is just churning afterwards. It wasn't like this at first." This sudden worsening of side effects after months of good tolerance was unusual. "Mr. Carter, has anything else changed?" I asked. "New medications, changes in health, diet, alcohol use?" He shook his head initially. "No, nothing I can think of..." Then he hesitated. "Well, I'm still taking the sildenafil, but..." # The Preemptive "Upgrade" His reluctance prompted me to ask directly, "Are you still taking the 50mg generic sildenafil that I prescribed, from the pharmacy?" He looked down, embarrassed. "Okay, no. Not for the last few weeks." He explained that despite the medication working well, he had spent hours reading online forums about ED. "It was kind of scary, Doc," he confessed, his anxiety palpable. "So many guys online kept talking about how sildenafil stops working fast. They said you build up tolerance really quickly, and the 50mg dose would probably fail me soon. They were saying you basically have to increase the dose proactively, or you'll be left high and dry." Influenced by this pervasive online narrative, Mr. Carter decided to act before his current, effective dose supposedly failed him. "Some of the forum guys recommended getting [Fildena 100 mg](https://www.imedix.com/drugs/fildena/) online," he admitted. "Said it was stronger, easily available, and basically the same stuff. So, I figured I should 'get ahead of the curve,' you know? Start the 100mg dose before the 50mg stopped working, so I wouldn't have any gap in performance." He ordered the Fildena 100 mg online and, without consulting me, simply switched himself from his well-tolerated 50mg prescription to the higher-dose, unregulated product, based purely on anticipated tolerance fueled by online fearmongering. # Debunking the Tolerance Myth I needed to address both his actions and the underlying misinformation. "Mr. Carter," I said firmly but calmly, "let's clear something up immediately. The idea that significant tolerance to sildenafil develops rapidly, requiring proactive dose increases like this, is largely a myth, especially over just a few months when a dose is working well. While some minor adjustments might be needed over long periods or if underlying conditions worsen, the scenario described on those forums is not typical pharmacological reality." "You acted preemptively," I continued, "based on fear generated by inaccurate online anecdotes. You switched from a dose that was working well and was well-tolerated, to a higher dose of an unregulated medication that you didn't actually need. The severe headaches, flushing, and indigestion you're experiencing now? Those are almost certainly the direct result of taking an unnecessarily high 100mg dose of sildenafil, compounded by the fact that we have no idea about the true dosage or purity of the Fildena you bought online." # Returning to Rational Dosing Mr. Carter looked taken aback, then relieved. The idea that he didn't need to constantly worry about imminent tolerance failure was clearly news to him. He also looked chagrined, realizing he'd subjected himself to significant discomfort based on unfounded fears. "So... the 50mg probably would have kept working?" he asked. "Most likely, yes," I confirmed. "And if, down the line, you genuinely felt the efficacy was decreasing, the correct approach would be to come talk to me. We could then assess the situation properly and decide together if a medically supervised dose increase was warranted, using legitimate medication." He readily agreed to discard the remaining Fildena 100 mg and go back to his original 50mg prescription, filled at his trusted pharmacy. He understood that any future dose adjustments needed to be driven by actual clinical need and discussed with me, not dictated by anxieties stoked on internet forums. # Reflection: The Danger of Anticipatory Self-Medication Mr. Carter's experience was a classic example of how online misinformation can create a negative feedback loop of anxiety and risky self-medication. The pervasive myth of rapid sildenafil tolerance, amplified in online echo chambers, caused him to distrust his own positive experience and proactively escalate his dose using an unregulated product. This unnecessary escalation led directly to significant adverse effects, proving the danger of acting on anticipated problems rather than actual ones. It underscored the importance of providing patients with accurate pharmacological information to counter online myths and empowering them to trust their own experience under medical guidance, rather than jumping onto a potentially harmful tolerance treadmill based on unfounded internet fears.