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# System prepended metadata

title: Substance Use Disorders

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# Substance Use Disorders 
- Dsm-5 : symptoms occuring within a 12-month period
- Symptoms : 
    - More than intended
    - Unsuccessful quiting 
    - Life revolves around drug (Obtaining,use or recovery)
    - Cravings 
    - Obligation failure due to drug 
    - Recurrent use in face of social reprimands
    - Giving up activities to use drug 
    - Use even when known to be harmful
    - Need for more amounts of drug (**Tolerance**)
    - Withdrawal 

## Knowledge About Alcohol Abuse
- Alcohol Dehydrogenase breaks down alcohol, more in men than women
- Serotonin link (Impulse control)
- Negative emotionality (neuroticism)
- Naltrexone ( Antagonist drug [Blocks Pleasure of Drug] ) 
- Acamprosate - Reduces cravings (Gaba Agonist [More Gaba])
- Antabuse - makes alcohol use unpleasant, buildup of acetaldehyde
### **Wernicke-Korsakoff Syndrome:** 
Anterograde Amnesia from long-term amnesia.
### Alcohol Use Guidelines 
* daily max = 2 drinks Woman, 3 drinks man 
* weekly max = 10 Woman, 15 man 
* Non drinking days 
* No drinking while vehicle 
* No drinking pregnant 
* Shouldnt drink child

## Barbiturates and Benzodiazepines 
- Depressants (inhibit neurotransmitters)
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