# Substance Use Disorders
- Dsm-5 : symptoms occuring within a 12-month period
- Symptoms :
- More than intended
- Unsuccessful quiting
- Life revolves around drug (Obtaining,use or recovery)
- Cravings
- Obligation failure due to drug
- Recurrent use in face of social reprimands
- Giving up activities to use drug
- Use even when known to be harmful
- Need for more amounts of drug (**Tolerance**)
- Withdrawal

## Knowledge About Alcohol Abuse
- Alcohol Dehydrogenase breaks down alcohol, more in men than women
- Serotonin link (Impulse control)
- Negative emotionality (neuroticism)
- Naltrexone ( Antagonist drug [Blocks Pleasure of Drug] )
- Acamprosate - Reduces cravings (Gaba Agonist [More Gaba])
- Antabuse - makes alcohol use unpleasant, buildup of acetaldehyde
### **Wernicke-Korsakoff Syndrome:**
Anterograde Amnesia from long-term amnesia.
### Alcohol Use Guidelines
* daily max = 2 drinks Woman, 3 drinks man
* weekly max = 10 Woman, 15 man
* Non drinking days
* No drinking while vehicle
* No drinking pregnant
* Shouldnt drink child

## Barbiturates and Benzodiazepines
- Depressants (inhibit neurotransmitters)
-