---
# System prepended metadata

title: Adv_Biostat
tags: [BioStat]

---

Adv_Biostat
===

###### tags: `BioStat`

- [2020.12.25](https://hackmd.io/@c64/SyjajQr6P)
    - RCT vs. RWD
    - Study Design和Data Analysis的重要性

- [2020.12.26](https://hackmd.io/@c64/Hk5__7rpD)
    - Study Design
    - Phase III Trials: three types of design
    - MCMC: Metropolis-Hasting algorithm


- [2020.12.27](https://hackmd.io/@c64/H1NZ2QSaD)
    - Sample Size Determination
    - Randomization與Balance
        - Biased Coin
        - Permuted Block Randomization
    - Data Analysis
        - MCMC: Gibbs Sampling
        - Regression Analysis

- [2020.12.28](https://hackmd.io/@c64/ryOHh7HpP)
    - Randomization
        - Stratiﬁed permuted block randomization
        - Adaptive Randomisation
            - Minimization Randomisation
            - Biased Urn Model
    - Trial Monitoring (GO or NO GO)
        - Repeated Testing for Signiﬁcance
        - Group Sequential Methods
        - Curtailed Sampling Procedures
        - Conditional Power
    - 期末作業說明
