---
# System prepended metadata

title: Lipoprotein A - aka Lp(a)
tags: [lipids, signals]

---

# Lipoprotein A - aka Lp(a)

## About

Lipoprotein(a), often abbreviated as Lp(a), is a specific type of lipoprotein particle in your blood. Here's a breakdown of what it is and its connection to cardiovascular health:

**Structure and Function:**

* Similar to LDL: Lp(a) shares similarities with LDL ("bad") cholesterol because it also carries cholesterol. However, it has an additional unique feature.
* Extra Piece: Lp(a) has an apo(a) protein attached to the LDL particle. This apo(a) protein is structurally similar to a protein involved in blood clotting.

**Cardiovascular Risk:**

* Potential Threat: Elevated Lp(a) levels are considered a risk factor for cardiovascular disease (CVD), particularly atherosclerosis (plaque buildup in arteries). 
* Why the Concern? The apo(a) protein on Lp(a) might contribute to the development of atherosclerosis in a couple of ways:
    * Increased Plaque Buildup: It may promote the adhesion of Lp(a) particles to the artery walls, potentially accelerating plaque formation.
    * Clot Formation: The similarity of apo(a) to a clotting protein might contribute to blood clot formation within narrowed arteries, further increasing CVD risk.

## How to lower it

Sadly, there is no known way to lower it. The best we can do is try to lower [Apolipoprotein B - aka apoB](/KOC6AK1TS-iWBCj6ra-bow), which can reduce our risk of cardeovascular disease.


