# How Spravato Can Offer New Hope for Treatment-Resistant Depression Spravato, also known by its generic name esketamine, is a breakthrough nasal spray medication approved by the FDA for individuals suffering from treatment-resistant depression (TRD). Unlike traditional antidepressants, Spravato works differently by targeting the NMDA receptor in the brain, offering fast and effective relief for patients who haven't responded to other medications. At Lotus Psychiatry and Wellness, we are proud to offer **[Spravato](https://lotuspsychiatryandwellness.com/spravato/)** as part of our comprehensive psychiatric treatment options for adults dealing with severe, persistent depression. ## How Spravato Works Spravato is a nasal spray administered under the supervision of a qualified medical professional in a certified clinic like Lotus Psychiatry and Wellness. Once administered, it affects glutamate activity in the brain—a neurotransmitter involved in mood regulation. This action helps restore synaptic connections and provides rapid improvement in depressive symptoms, sometimes within hours or days. Spravato is typically used in conjunction with an oral antidepressant, and the treatment plan is carefully personalized based on your response and needs. ## Who is a Candidate for Spravato? You may be a candidate for Spravato treatment if: You’ve tried two or more antidepressants without relief You have been diagnosed with major depressive disorder (MDD) You are not experiencing psychosis You are under the supervision of a psychiatrist Before starting Spravato, our team at Lotus Psychiatry and Wellness conducts a full psychiatric evaluation to determine if it's the right treatment path for you. ## What to Expect During Spravato Treatment Spravato treatment involves in-office sessions typically held twice a week during the initial phase. During each session: The medication is self-administered under supervision. You are monitored for at least two hours to ensure safety and track response. You are not allowed to drive for the rest of the day, so transportation arrangements are required. Many patients report feeling relief from symptoms within a few sessions, though full benefits are often seen after several weeks of consistent treatment. ## Why Choose Lotus Psychiatry and Wellness for Spravato? Lotus Psychiatry and Wellness is a certified Spravato treatment center dedicated to providing safe, compassionate, and effective care. When you choose us, you receive: Expert evaluation from board-certified psychiatrists Personalized treatment planning and follow-up care Comfortable, private treatment rooms Ongoing support throughout your healing journey Our mission is to provide evidence-based treatments that offer genuine relief and improve your quality of life. ### Take Control of Your Mental Health Today If depression has been controlling your life, **[Spravato](https://lotuspsychiatryandwellness.com/spravato/)** could be the innovative solution you’ve been waiting for. At Lotus Psychiatry and Wellness, we are committed to helping you find lasting relief through the most advanced treatments available. Contact us today to learn more about Spravato and schedule your consultation. Let us help you regain control and start your path to mental wellness.