#### Weakly-Supervised semantic segmentation for histopathology images based on dataset synthesis and feature consistency constraints
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- homogenity of medical images

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### WSSS for medical images
- multiple instance learning (MIL)
- CAM-based methods
- HistoSegNet (GradCAM)
- WSSS-tissue
- C-CAM (MRI)
- OEEM
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- **Problems:** though the above methods can alleviate fuzzy boundary problem to some extent, the gap between classification and segmentation still exists
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- PistoSeg framework

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- pseudo-mask refining module


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- Loss design



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- performance on WSSS4LUAD / BCSS-WSSS

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- ablations on losses

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- ablations on refining module on different CAMs

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- ablations on precise segmentation inputs

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